Health 18 June 2026 Daily Monitor (Uganda)

Sickle Cell Disease Claims 16% of Uganda's Under-Five Deaths

Sickle cell disease is now responsible for approximately 16 percent of all child deaths under the age of five in Uganda, a concerning rise that health officials are urging the public to address through increased awareness and testing. Source: https://www.monitor.co.ug/uganda/news/national/sickle-cell-disease-causes-16-percent-of-under-five-deaths-in-uganda-govt-says-5501706

The Ministry of Health in Uganda has revealed that sickle cell disease is a significant contributor to under-five mortality, accounting for around 16 percent of these tragic deaths. This figure represents a slight increase from previous years, underscoring the persistent challenge the condition poses to public health.

Estimates suggest that each year, approximately 20,000 Ugandan babies are born with sickle cell disease. Sadly, a substantial number, between 6,000 and 9,000, do not survive past their fifth birthday. Health officials emphasize that improving the care and survival rates for these children is crucial for reducing the nation’s overall under-five mortality rate.

Adding to the concern, an estimated six to seven million Ugandans carry the sickle cell trait. This means that while they may not have the disease themselves, they can pass the trait to their children, increasing the risk of the child inheriting sickle cell disease. The prevalence of the trait is particularly high in certain regions, reaching around 20 percent in parts of northern and eastern Uganda.

In response, the Ministry of Health is intensifying efforts to promote newborn screening and premarital counseling. The aim is to empower couples with knowledge of their genetic status to make informed decisions and prevent the transmission of sickle cell disease. Expanding community screening services, especially in remote areas, is also a priority for early diagnosis and treatment.

Access to essential medicines, such as Hydroxyurea, which helps manage complications, remains a critical challenge. Health facilities are being urged to include this vital medication in their procurement plans. Early diagnosis, consistent treatment, and heightened public awareness are identified as key strategies to combat sickle cell disease, reduce fatalities, and improve the quality of life for those affected.

This information is based on reports from the Ministry of Health and health officials in Uganda.